Delport S D, van den Berg J H
Department of Paediatrics, Kalafong Hospital.
S Afr Med J. 1998 Jan;88(1):43-4.
To determine the validity, predictive value and accuracy of the rapid plasma reagin card test performed on site to diagnose active syphilis in pregnant women so that immediate treatment can be offered to prevent congenital syphilis.
Open, descriptive study.
Antenatal clinic, Mamelodi Hospital, Pretoria.
Four hundred and seventy-four pregnant women attending the antenatal clinic for the first time were entered into the study.
A rapid plasma reagin test was performed on site with no specialised equipment and the results were compared with those of the reference laboratory.
In the event of rapid plasma reagin titres of 1:8 and higher, indicative of active syphilis, the on-site rapid plasma reagin test had a sensitivity of 90.5%. The test had a sensitivity of 100% if the rapid plasma reagin titres were 1:16 and higher.
The on-site rapid plasma reagin test identified all women with rapid plasma reagin titres higher than 1:8. This implies that all women whose fetuses were in danger of acquiring congenital syphilis were identified at the clinic and could be treated immediately.
确定现场进行的快速血浆反应素卡片试验诊断孕妇活动性梅毒的有效性、预测价值和准确性，以便能立即提供治疗以预防先天性梅毒。
开放性描述性研究。
比勒陀利亚马梅洛迪医院产前诊所。
474名首次到产前诊所就诊的孕妇纳入本研究。
在无专门设备的情况下现场进行快速血浆反应素试验，并将结果与参考实验室的结果进行比较。
对于快速血浆反应素滴度为1:8及以上（表明活动性梅毒）的情况，现场快速血浆反应素试验的敏感性为90.5%。如果快速血浆反应素滴度为1:16及以上，该试验的敏感性为100%。
现场快速血浆反应素试验识别出了所有快速血浆反应素滴度高于1:8的女性。这意味着在诊所识别出了所有胎儿有感染先天性梅毒风险的女性，她们可以立即接受治疗。
