Schiffenbauer J, Soos J, Johnson H
Dept of Medicine, University of Florida, Gainesville 32610, USA.
Immunol Today. 1998 Mar;19(3):117-20. doi: 10.1016/s0167-5699(97)01199-7.
The ability of superantigens (SAgs) to activate the immune system suggests that they may play a role in the course of autoimmune disorders. Here, Joel Schiffenbauer and colleagues review evidence from animal models of autoimmunity, as well as human data that support this hypothesis, and propose a model for SAg involvement in autoimmune disorders.
超抗原(SAgs)激活免疫系统的能力表明它们可能在自身免疫性疾病的病程中发挥作用。在此,乔尔·希芬鲍尔及其同事回顾了来自自身免疫性动物模型的证据以及支持这一假设的人类数据,并提出了一个超抗原参与自身免疫性疾病的模型。