新生儿低血糖的影像学表现。
Imaging patterns of neonatal hypoglycemia.
作者信息
Barkovich A J, Ali F A, Rowley H A, Bass N
机构信息
Department of Radiology, University of California, San Francisco, 94143, USA.
出版信息
AJNR Am J Neuroradiol. 1998 Mar;19(3):523-8.
PURPOSE
Our purpose was to report the patterns of injury observed in five patients who suffered brain damage consequent to neonatal hypoglycemia.
METHODS
The imaging studies and clinical records of five patients with brain damage caused by neonatal hypoglycemia were reviewed retrospectively. Patterns of injury were compared with those described in the literature and those seen in neonatal hypoxic-ischemic injury.
RESULTS
Diffuse cortical and subcortical white matter damage was seen, with the parietal and occipital lobes affected most severely. Globus pallidus injury was present in one patient who had the most severe cortical injury.
CONCLUSION
We found a specific pattern of injury that correlates well with the sparse pathologic and imaging reports on neonatal hypoglycemia. We speculate that the patterns of damage are the result of regional hypoperfusion and excitatory toxicity with cell-type-specific injury.
目的
我们的目的是报告5例因新生儿低血糖导致脑损伤患者的损伤模式。
方法
回顾性分析5例因新生儿低血糖导致脑损伤患者的影像学研究和临床记录。将损伤模式与文献中描述的以及新生儿缺氧缺血性损伤中所见的模式进行比较。
结果
可见弥漫性皮质和皮质下白质损伤，顶叶和枕叶受影响最严重。1例皮质损伤最严重的患者出现苍白球损伤。
结论
我们发现了一种特定的损伤模式，与关于新生儿低血糖的稀少病理和影像学报告相关性良好。我们推测损伤模式是区域灌注不足和兴奋性毒性导致细胞类型特异性损伤的结果。
Zotero 插件