[氯氮平与奋乃静致死性中毒。病例报告]
[Fatal poisoning with clozapine and perazine. A case report].
作者信息
Ganssmann B, Skopp G, Aderjan R, Mattern R
机构信息
Institut für Rechtsmedizin und Verkehrsmedizin, Universität Heidelberg.
出版信息
Arch Kriminol. 1998 Jan-Feb;201(1-2):11-20.
PMID:9541713
Abstract
An intoxication following an apparent overdose of clozapine (Leponex) and perazine (Taxilan) is reported. There was a wide range of variation in postmortem blood and tissue concentrations of clozapine, desmethyclozapine and perazine. Clozapine/norclozapine blood and tissue ratios and perazine-pill-fragments in the gastric content could be used as a sign of suspected acute clozapine and perazine overdose.
摘要
据报道，有一例因明显过量服用氯氮平（氯扎平）和奋乃静（羟哌氯丙嗪）导致的中毒事件。氯氮平、去甲氯氮平和奋乃静的尸检血液及组织浓度存在广泛差异。氯氮平/去甲氯氮平的血液与组织比率以及胃内容物中的奋乃静药片状碎片可作为疑似急性氯氮平和奋乃静过量的迹象。
Zotero 插件