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[加泰罗尼亚地区孕产妇HIV感染率(1994年):非相关匿名新生儿筛查结果。VIHNADO研究小组]

[Prevalence of maternal HIV infection in Catalonia (1994): results of non-related anonymous neonatal screening. VIHNADO Group].

作者信息

Vall Mayans M, Maya A, Matas L, Casabona J

机构信息

Centre d'Estudis Epidemiològics sobre la Sida de Catalunya, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona.

出版信息

Med Clin (Barc). 1998 Feb 7;110(4):128-31.

PMID:9541901
Abstract

BACKGROUND

Spain has the highest incidence rate of AIDS in Europe. Catalonia contributes with around 30% of the AIDS cases detected in Spain. From 1990 to 1994 the AIDS heterosexual transmission category increased from 9.6% to 14.6% in Catalonia. The objective of the study was to determine the HIV prevalence in a heterosexual population of pregnant women.

SUBJECTS AND METHODS

Unlinked anonymous HIV screening by means of an agglutination assay and an enzyme immunoassay of eluates of dried blood spots from nearly half of the neonates born in Catalonia during 1994.

RESULTS

HIV testing was done on 21,074 neonates. Overall HIV prevalence was 0.32% (95% CI: 0.25-0.40). It varied from 0.45% in Barcelona, 0.38-0.29% in the health regions around Barcelona, to 0.20-0.09% in the rest. The mean age of HIV infected women was younger (27) than that of the seronegative ones (29) (p < 0.001). The highest prevalence was 0.61% in women aged 20-24 years.

CONCLUSIONS

The HIV prevalence in the heterosexual population of pregnant women in Catalonia is among the highest in Europe. Preventive efforts must begin with schoolchildren and be directed to adolescents and young women. It is convenient that women who want to become pregnant and mothers receiving antenatal care have access to voluntary confidential HIV testing.

摘要

背景

西班牙是欧洲艾滋病发病率最高的国家。加泰罗尼亚地区的艾滋病病例约占西班牙确诊病例的30%。1990年至1994年期间,加泰罗尼亚地区艾滋病异性传播病例的比例从9.6%增至14.6%。本研究的目的是确定孕妇异性恋人群中的艾滋病毒感染率。

研究对象与方法

采用凝集试验和酶免疫法对1994年在加泰罗尼亚出生的近半数新生儿的干血斑洗脱液进行非关联匿名艾滋病毒筛查。

结果

对21,074名新生儿进行了艾滋病毒检测。总体艾滋病毒感染率为0.32%(95%置信区间:0.25 - 0.40)。感染率在巴塞罗那为0.45%,巴塞罗那周边卫生区域为0.38% - 0.29%,其他地区为0.20% - 0.09%。感染艾滋病毒的女性平均年龄(27岁)低于血清阴性女性(29岁)(p < 0.001)。20 - 24岁女性的感染率最高,为0.61%。

结论

加泰罗尼亚孕妇异性恋人群中的艾滋病毒感染率在欧洲名列前茅。预防工作必须从学童抓起,并针对青少年和年轻女性。希望怀孕的女性以及接受产前护理的母亲能够获得自愿保密的艾滋病毒检测,这很有必要。

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