Hoepelman I M, Sachs A P, Visser M R, Lammers J W
Afd. Interne Geneeskunde, Academisch Ziekenhuis, Utrecht.
Ned Tijdschr Geneeskd. 1997 Aug 16;141(33):1597-601.
There are three Anglo-Saxon guidelines for the management of patients with a community-acquired pneumonia: an American, a British and a Canadian one. The guidelines correspond fairly well. There is a subdivision into categories according to whether the patients are treated at home (formerly healthy patients younger than 60 years versus patients with pre-existent disease or aged 60 years and more) or in the hospital (patients not needing intensive care versus those who do need it). For each category the most common causative micro-organisms are listed together with recommended antibiotic treatment. The Canadian guidelines have nursing home patients as a separate category because of slightly different causative organisms due to frequent microaspiration. The guidelines are applicable to the situation in the Netherlands, with a few exceptions: antibiotic resistance is not a major problem in the Netherlands (as yet), and contrary to what the guidelines state an agent with activity against Pseudomonas aeruginosa is not necessary; the same agents as in category III can be prescribed in these patients. A macrolide or azalide antibiotic is advisable for intensive care patients in view of the possibility of infection with Legionella pneumophila or Mycoplasma pneumoniae.
有三项关于社区获得性肺炎患者管理的盎格鲁-撒克逊指南:一项美国指南、一项英国指南和一项加拿大指南。这些指南相当一致。根据患者是在家接受治疗(以前健康的60岁以下患者与有基础疾病或60岁及以上患者)还是在医院接受治疗(不需要重症监护的患者与需要重症监护的患者)进行分类。对于每个类别,列出了最常见的致病微生物以及推荐的抗生素治疗方法。由于养老院患者因频繁微吸入导致致病微生物略有不同,加拿大指南将其作为一个单独类别。这些指南适用于荷兰的情况,但有一些例外:抗生素耐药性在荷兰(目前)不是一个主要问题,与指南所述相反,对铜绿假单胞菌有活性的药物并非必要;这些患者可以使用与第三类相同的药物。鉴于存在感染嗜肺军团菌或肺炎支原体的可能性,对于重症监护患者,建议使用大环内酯类或氮杂内酯类抗生素。