Richter H, Jostarndt L, Tichai I, Thermann M
Chirurg. 1976 Jun;47(6):328-30.
Elevation of the intraluminar pressure of rabbit ileum lowers the oxygen supply of the bowel wall in a pressure dependent manner. After decompression local PO2 exceeds the initial values. The infusion of Rheomacrodex-Sorbit induces an increase of local PO2 in the nondistended ileum. The reaction is enhanced in the distended bowel. The application of glucagon does not influence tissue PO2 significantly in either the distended or the undistended bowel. The infusion of Rheomacrodex-Sorbit as well as decompression of the distended bowel are recommended to improve oxygen supply of bowel wall in ileus.
兔回肠腔内压力升高会以压力依赖的方式降低肠壁的氧气供应。减压后局部氧分压超过初始值。输注低分子右旋糖酐 - 山梨醇会使未扩张回肠的局部氧分压升高。在扩张的肠段中这种反应增强。无论在扩张还是未扩张的肠段中,应用胰高血糖素对组织氧分压均无显著影响。建议输注低分子右旋糖酐 - 山梨醇以及对扩张的肠段进行减压,以改善肠梗阻时肠壁的氧气供应。