Stadler J, Müller W, Henche H R, Sauer R
Chirurg. 1976 Jun;47(6):336-44.
Eight pathologic fractures of benign and 52 of malignant origin are reported. Open reduction and rigid internal fixation should be performed to give the patient the use of his affected limb as soon as this can be accomplished. Treatment consists of internal fixation in lesions of the shaft and prosthetic replacement in the case of lesions near joints. Only very rarely a primary amputation must be performed. Malignant fractures are most frequently caused by metastases from breast cancers. The treatment will at least make nursing easier, and three-quarters of these patients can be mobilized. The combination of surgical treatment and radiotherapy is discussed. In spite of this approach the average time of survival of 14 months is short because a pathological fracture due to a malignant tumor is a late symptom of the disease.
报告了8例良性病理性骨折和52例恶性病理性骨折。应尽快进行切开复位和坚强内固定，以便患者能够使用其患肢。治疗方法包括对骨干病变进行内固定，对关节附近病变进行假体置换。只有极少数情况下必须进行一期截肢。恶性骨折最常见的原因是乳腺癌转移。这种治疗至少会使护理更容易，并且四分之三的患者能够活动。文中讨论了手术治疗与放疗相结合的方法。尽管采用了这种方法，但平均14个月的生存期仍然较短，因为恶性肿瘤导致的病理性骨折是该疾病的晚期症状。
