Rimmelzwaan G F, de Jong J C, Bartelds A I, Claas E C, van Wijngaarden J K, Osterhaus A D
Nationaal Influenza Centrum van de WHO, Erasmus Universiteit, afd. Virologie, Rotterdam.
Ned Tijdschr Geneeskd. 1997 Sep 6;141(36):1743-7.
The first indication of flu activity in the Netherlands in the 1996/'97 season was the isolation of an A/H3N2 influenza virus in week 48 of 1996. In subsequent weeks influenza viruses were isolated sporadically. The clinical influenza activity increased from week I of 1997 and reached its peak in week 4 of 1997. Simultaneously with the increase of clinical influenza activity, an increasing number of influenza viruses were isolated. The epidemic had a relatively small extent. Initially, A/H3N2 influenza viruses were predominant, but in the second half of the epidemic an increasing number of influenza B viruses were isolated as well. The A/H3N2 viruses were antigenically fairly strongly distinct from the variants prevalent in the preceding years. This season influenza A/HINI viruses did not play a significant role and only one virus of this subtype was isolated. All influenza A/H3N2, A/HINI and B viruses isolated were antigenically similar to the vaccine strains.
1996/97流感季荷兰流感活动的首个迹象是在1996年第48周分离出一株A/H3N2流感病毒。在随后几周，流感病毒呈零星分离状态。临床流感活动从1997年第1周开始增加，并于1997年第4周达到高峰。随着临床流感活动的增加，分离出的流感病毒数量也在增多。此次疫情范围相对较小。起初，A/H3N2流感病毒占主导，但在疫情后半段，也分离出了越来越多的B型流感病毒。A/H3N2病毒在抗原性上与前几年流行的毒株有相当大的差异。本季A/H1N1流感病毒未发挥重要作用，仅分离出1株该亚型病毒。所有分离出的A/H3N2、A/H1N1和B型流感病毒在抗原性上均与疫苗株相似。
