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[心力衰竭中血小板减少症的发生率及发病机制]

[Frequency and pathogenis of thrombocytopenia in cardiac failure].

作者信息

Heck J, Keitel K, Wŭsthoff D, Gehrmann G

出版信息

Dtsch Med Wochenschr. 1976 Sep 17;101(38):1381-4. doi: 10.1055/s-0028-1104277.

DOI:10.1055/s-0028-1104277
PMID:954598
Abstract

In 395 consecutively investigated patients with cardiac failure of varying aetiologythe platelet ocurt in venous blood was less than 100 000/mm(3) in 5.3% and below the 2s devaition (less than 136 000/mm (3)) in 19.2. The average platelet count of the whole group was 197 500 +/- 70 800/mm (3) which was significantly lower (P less than 0.001) than in normal controls (n = 128). In 6 patients a (51)Cr study of platelet kinetics was performed; the results support the conclusion that the faculatative thrombocytopenia in cardiac failure is mainly,but not exclusively, due to an increased uptake of platelets in the congested spleen.

摘要

在395例病因各异的心力衰竭患者中,连续调查发现,5.3%的患者静脉血中血小板计数低于100000/mm³,19.2%的患者低于2个标准差(低于136000/mm³)。全组患者的平均血小板计数为197500±70800/mm³,显著低于正常对照组(n = 128)(P<0.001)。对6例患者进行了血小板动力学的(51)铬研究;结果支持以下结论:心力衰竭时的继发性血小板减少主要但并非完全是由于充血脾脏对血小板的摄取增加所致。

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[Frequency and pathogenis of thrombocytopenia in cardiac failure].[心力衰竭中血小板减少症的发生率及发病机制]
Dtsch Med Wochenschr. 1976 Sep 17;101(38):1381-4. doi: 10.1055/s-0028-1104277.
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[Thrombocytopenia in heart failure].[心力衰竭中的血小板减少症]
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