英国幼驹感染泰泽氏病的4例病例。

Four cases of Tyzzer's disease in foals in England.

作者信息

Whitwell K E

出版信息

Equine Vet J. 1976 Jul;8(3):118-22. doi: 10.1111/j.2042-3306.1976.tb03313.x.

DOI:10.1111/j.2042-3306.1976.tb03313.x

Abstract

A rodent pathogen, Bacillus piliformis, has been recognised as causing a rapidly fatal hepatitis in 4 foals in England. The disease in foals has been recognised in America since 1973. A clinico-pathological account of the 4 cases is given and the differential diagnosis discussed. The 4 foals' ages fell within a very narrow range (24-34 days). Some of the properties of this unusual intracellular pathogen are reviewed. For the first time in the equine the bacillus was seen in association with myocardial lesions. There are marked differences in the epidemiology of the disease in the mouse and in the foal, which may result from the very different management practices in the 2 species. It is suggested that the dams of affected foals may be carriers of the disease.

摘要

一种啮齿动物病原体——丝状芽孢杆菌，已被认定为在英国导致4匹幼驹患上迅速致命的肝炎。自1973年以来，美国就已认识到幼驹中的这种疾病。本文给出了这4例病例的临床病理描述并讨论了鉴别诊断。这4匹幼驹的年龄范围非常狭窄（24 - 34天）。本文回顾了这种不寻常的细胞内病原体的一些特性。在马属动物中首次发现该杆菌与心肌病变有关。该疾病在小鼠和幼驹中的流行病学存在显著差异，这可能是由于这两个物种的管理方式截然不同所致。有人认为，患病幼驹的母马可能是该疾病的携带者。