Elangbam C S, Clevidence K J, Jackson C B, Holson J F
WIL Research Laboratories, A Subsidiary of Great Lakes Chemical Corporation, Ashland, Ohio 44805, USA.
Toxicol Pathol. 1998 Mar-Apr;26(2):290-3. doi: 10.1177/019262339802600216.
Duplications of the gastrointestinal tract are exceedingly rare in laboratory animals. We report a case of a communicating intestinal duplication in a 17-wk-old Sprague-Dawley (SD) rat. The duplication was present in the mesenteric border of the ileum, and both proximal and distal ends were communicated with the lumen of ileum. Histologically, the duplicated portion had a thick muscle wall and a mucosa similar to that of the small intestine. This is the first reported case of intestinal duplication in an SD rat.
胃肠道重复畸形在实验动物中极为罕见。我们报告一例17周龄的斯普拉格-道利(SD)大鼠发生的交通性肠重复畸形。重复畸形位于回肠系膜缘,其近端和远端均与回肠腔相通。组织学上,重复部分有厚的肌壁和类似于小肠的黏膜。这是首例报道的SD大鼠肠重复畸形病例。