Morimoto Y, Natsume H
Faculty of Pharmaceutical Sciences, Josai University.
Nihon Rinsho. 1998 Mar;56(3):649-56.
Organ level-targeting of anticancer drugs or other relating stimuli to tumor tissues and their circumstances is important in cancer therapy. The successful targeting results in the greater antitumor effect and the lower numerous side effects. Application of a magnet from the outside of body is a useful tool to increase the targeting efficacy. In this review paper, targeting technology utilizing magnetic microparticulate system for cancer therapy was introduced and the future on the magnetic targeting system was augured.
在癌症治疗中,将抗癌药物或其他相关刺激物在器官水平靶向肿瘤组织及其周围环境非常重要。成功的靶向可带来更强的抗肿瘤效果以及更少的副作用。从体外施加磁场是提高靶向效果的一种有用工具。在这篇综述论文中,介绍了利用磁性微粒系统进行癌症治疗的靶向技术,并对磁性靶向系统的未来进行了展望。