凋亡诱导的去唾液酸糖蛋白（ASGP）受体。它们在新生大鼠肝细胞中的免疫组织化学定位。
Asialoglycoprotein (ASGP) receptors induced by apoptosis. Their immunohistochemical localization in neonatal rat hepatocytes.
作者信息
Dini L
出版信息
Riv Biol. 1997;90(3):423-6.
PMID:9549405
Abstract
Immunohistochemical detection of asialoglycoprotein (ASGP) receptors has been performed on neonatal rat hepatocytes in primary cultures, incubated with TGF beta, TNF alpha and retinoic acid. These substances account for the increase in the rate of apoptosis of the cell cultures and for the increase of the expression of ASGP receptors. Both modifications are higher at 24 hours of incubation.
摘要
在原代培养的新生大鼠肝细胞中进行了去唾液酸糖蛋白（ASGP）受体的免疫组织化学检测，这些肝细胞与转化生长因子β（TGFβ）、肿瘤坏死因子α（TNFα）和视黄酸一起孵育。这些物质导致细胞培养物中凋亡率增加以及ASGP受体表达增加。两种变化在孵育24小时时更为明显。
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