Bhattacharya S K, Parikh A K, Das P K
Experientia. 1976 Aug 15;32(8):1039-40. doi: 10.1007/BF01933959.
Acetylcholine produced melanin aggregation and blanching of skin colour in Rana tigrina, the common Indian frog. The effects were more prolonged in frogs pretreated with an anticholinesterase agent. Acetylcholine effects were not antagonized by either m-cholinolytic (atropine) or n-cholinolytic (pentolinium) agents, but were markedly inhibited by procaine. The results have been discussed in the light of the well-known membrane-stabilizing effect of procaine.
乙酰胆碱可使印度常见青蛙——虎纹蛙的皮肤产生黑色素聚集并导致皮肤颜色变白。在用抗胆碱酯酶剂预处理过的青蛙中,这些效应持续时间更长。乙酰胆碱的效应既不能被m - 胆碱能阻断剂(阿托品)也不能被n - 胆碱能阻断剂(喷托铵)拮抗,但可被普鲁卡因显著抑制。已根据普鲁卡因众所周知的膜稳定作用对结果进行了讨论。