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黄腹鼹形田鼠(田鼠亚科)原始前列腺在器官培养中的发育;雄激素的作用(作者译)

[Development of the rudimentary prostates of Ellobius lutescens (Microtinae) in organ culture; effects of androgens (author's transl)].

作者信息

Stefan Y, Medilanski J

出版信息

Experientia. 1976 Aug 15;32(8):1074-6. doi: 10.1007/BF01933980.

Abstract

The structure of the rudimentary prostates of Ellobius lutescens is maintained intact after 6 days of organotypic culture in the absence of male hormones. Comparison with controls even shows a noticeable increase in the size of the epithelial cells. Adding male hormones to the culture medium does not modify the morphology of adult prostates, while it induces a sharp stimulation of immature prostates. In accordance with our previous results, these experiments show that the prostates of Ellobius lutescens lose their sensivity to androgens after puberty.

摘要

在没有雄性激素的情况下进行6天的器官型培养后,黄颈姬鼠未成熟前列腺的结构保持完整。与对照组相比,上皮细胞的大小甚至有明显增加。向培养基中添加雄性激素不会改变成年前列腺的形态,而会对未成熟前列腺产生强烈刺激。根据我们之前的结果,这些实验表明,黄颈姬鼠的前列腺在青春期后对雄激素失去敏感性。

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