Shaha A R, Jaffe B M
Department of Surgery, Health Science Center at Brooklyn, State University of New York, USA.
Am J Otolaryngol. 1998 Mar-Apr;19(2):113-7. doi: 10.1016/s0196-0709(98)90106-5.
Even though thyroid surgery is generally quite safe, permanent hypoparathyroidism is a very distressing complication. The incidence of hypoparathyroidism is directly proportional to the extent of thyroidectomy, and inversely proportional to the experience of the surgeon. It is also related to the extent of invasion of thyroid cancer and of the degree of dissection in the tracheo-esophageal groove. The incidence reported in the literature varies between 1% to 29%. Total thyroidectomy results in a higher incidence of hypoparathyroidism.
This report describes experiences with 600 thyroidectomies over a period of 11 years. The major indications for surgery included suspicion or proof of malignancy, compression symptoms, and substernal goiters. Twenty-six patients underwent surgery for Graves' disease. There were 221 men and 379 women, ranging in age from 16 to 89 years; 88% of the patients had benign disease, whereas 12% of the patients had malignant pathology. The surgical procedures included 62 total thyroidecotmies, 188 subtotal thyroidectomies, and lobectomy and isthmectomy in 350 patients.
Meticulous tracheo-esophageal groove dissection, identification of parathyroids and their preservation, including the blood supply, was routine in each case. Even in patients undergoing unilateral lobectomy, every effort was made to preserve the parathyroids. If any of the parathyroids or its blood supply was injured, it was autotransplanted in the sternomastoid muscle. Only two patients developed temporary hypoparathyroidism.
Parathyroid autotransplantation is performed whenever one or more of the parathyroids are damaged. Parathyroid preservation during thyroid surgery is crucial in the overall management of thyroid diseases.
尽管甲状腺手术总体上相当安全,但永久性甲状旁腺功能减退是一种非常令人苦恼的并发症。甲状旁腺功能减退的发生率与甲状腺切除术的范围成正比,与外科医生的经验成反比。它还与甲状腺癌的侵犯范围以及气管食管沟的解剖程度有关。文献报道的发生率在1%至29%之间。全甲状腺切除术导致甲状旁腺功能减退的发生率更高。
本报告描述了11年间600例甲状腺切除术的经验。手术的主要适应证包括怀疑或证实为恶性肿瘤、压迫症状和胸骨后甲状腺肿。26例患者因格雷夫斯病接受手术。有221名男性和379名女性,年龄在16至89岁之间;88%的患者患有良性疾病,而12%的患者有恶性病理。手术方式包括62例全甲状腺切除术、188例次全甲状腺切除术以及350例患者的甲状腺叶切除术和峡部切除术。
在每例手术中,仔细进行气管食管沟解剖、识别甲状旁腺并对其进行保留(包括血供)是常规操作。即使是接受单侧甲状腺叶切除术的患者,也会尽一切努力保留甲状旁腺。如果甲状旁腺或其血供受到损伤,会将其自体移植到胸锁乳突肌中。只有两名患者出现了暂时性甲状旁腺功能减退。
当一个或多个甲状旁腺受损时,进行甲状旁腺自体移植。在甲状腺手术中保留甲状旁腺对于甲状腺疾病的整体管理至关重要。