Kuwabara P E
Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK.
Curr Biol. 1998 Apr 9;8(8):R278-81. doi: 10.1016/s0960-9822(98)70172-1.
Caenorhabditis elegans hermaphrodites switch from making sperm to oocytes. This switch involves repression of fem-3 mRNA, mediated by a protein that binds RNA through a conserved motif; a similar motif mediates RNA binding by the Drosophila pattern-regulatory protein Pumilio.
秀丽隐杆线虫雌雄同体个体从产生精子转变为产生卵母细胞。这种转变涉及对fem - 3信使核糖核酸(mRNA)的抑制,这是由一种通过保守基序与RNA结合的蛋白质介导的;类似的基序介导果蝇模式调节蛋白Pumilio与RNA的结合。