Lehmann K J, Diehl S J, Lachmann R, Georgi M
Institut für Klinische Radiologie, Klinikum Mannheim der Universität Heidelberg.
Rofo. 1998 Mar;168(3):211-6. doi: 10.1055/s-2007-1015115.
A prospective study was performed to evaluate the accuracy of dual phase helical CT in suspected pancreatic cancer.
Within one year 136 patients underwent helical CT with arterial and portal venous scans after bolus tracking and NaCl bolus injection. Evidence of pancreatic cancer and assessment of resectability were recorded using a standardised protocol. Suspected benign disease was verified by follow-up examination and clinical data, suspected malignant disease was correlated with biopsy or surgery.
For the detection of tumor the overall concordance was 92%, the sensitivity 98% and the specificity 70% (6 false positive, 1 false negative). Resectability was correctly assessed in 90% with a sensitivity of 92% and a specificity of 88% (4 false positive, 4 false negative). Vascular invasion was detected correctly in 91% (veins)-94% (arteries), lymph node invasion in 67% and liver metastasis in 94%.
Dual phase helical CT is a very reliable tool in the assessment of resectability in pancreatic cancer.
进行一项前瞻性研究以评估双期螺旋CT在疑似胰腺癌诊断中的准确性。
在一年时间内，136例患者在团注追踪和注射生理盐水团注后接受了动脉期和门静脉期的螺旋CT扫描。采用标准化方案记录胰腺癌的证据及可切除性评估情况。疑似良性疾病通过随访检查和临床数据得以证实，疑似恶性疾病则与活检或手术结果进行对照。
对于肿瘤检测，总体一致性为92%，敏感性为98%，特异性为70%（6例假阳性，1例假阴性）。可切除性评估的正确率为90%，敏感性为92%，特异性为88%（4例假阳性，4例假阴性）。静脉血管侵犯的正确检测率为91%，动脉血管侵犯为94%，淋巴结侵犯为67%，肝转移为94%。
双期螺旋CT是评估胰腺癌可切除性的一种非常可靠的工具。
