Sher G, Katz M
Fertil Steril. 1976 Aug;27(8):886-91. doi: 10.1016/s0015-0282(16)42020-0.
The purpose of this study was to investigate and treat a group of patients referred for "idiopathic" infertility in whom no apparent cause for infertility, apart from inadequate cervical mucus, was found. Hormone investigations revealed that these patients could be divided into two groups: those with low sex steroid profiles despite apparent ovulation, and a second group with normal sex steroid profiles. All patients were treated with ovulation-inducing agents in an attempt to produce "controlled" ovarian hyperstimulation and an improved cervical mucus. Four of six patients conceived. The rationale behind the use of ovulation-inducing agents in this situation is discussed.
本研究的目的是调查并治疗一组因“特发性”不孕前来就诊的患者,这些患者除宫颈黏液不足外,未发现明显的不孕原因。激素检查显示,这些患者可分为两组:一组尽管有明显排卵,但性类固醇水平较低;另一组性类固醇水平正常。所有患者均接受促排卵药物治疗,试图实现“控制性”卵巢过度刺激并改善宫颈黏液。6名患者中有4名受孕。本文讨论了在这种情况下使用促排卵药物的基本原理。