Heckmann M, Ceballos-Baumann A, Schaller M, Plewig G
Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, München.
Hautarzt. 1998 Feb;49(2):87-90. doi: 10.1007/s001050050705.
Based on its unique botulinum toxin is referred to as the most poisonous poison. Its specific inhibition of the acetyl-cholin-dependent neuromuscular transmission is used by ophthalmologists and neurologists for the relaxation of spastic or dystonic muscles, preferably in muscle groups in the head and neck area. Analogously, it is being used by dermatologists to remove facial wrinkles by paralyzing mimic muscles which account for mechanically induced wrinkling. Apart from this purely cosmetic use, botulinum toxin has gained recent attention in dermatology as a potent treatment modality for circumscribed hyperhidrosis.
基于其独特性，肉毒杆菌毒素被称为最毒的毒物。眼科医生和神经科医生利用其对乙酰胆碱依赖性神经肌肉传递的特异性抑制作用，来放松痉挛或张力障碍性肌肉，尤其适用于头颈部区域的肌肉群。类似地，皮肤科医生利用它来麻痹导致机械性皱纹的表情肌，从而消除面部皱纹。除了这种纯粹的美容用途外，肉毒杆菌毒素最近在皮肤科作为一种治疗局限性多汗症的有效治疗方式而受到关注。
