Histology of the endometrium in long-term use of a sequential oral contraceptive.
作者信息
Kreutner A, Johnson D, Williamson H O
出版信息
Fertil Steril. 1976 Aug;27(8):905-10. doi: 10.1016/s0015-0282(16)42010-8.
PMID:955133
Abstract
Non-atypical adenomatous hyperplasia was found in 13.5% of 111 biopsies obtained from long-term, predominantly black, users of Oracon. An association between length of time of use (95 cycles for those with adenomatous hyperplasia versus 73 for those without) and the development of adenomatous hyperplasia was noted, but there was no association with hypertension or obesity. Cystic glandular dilatation was seen in 63% but was not thought to represent hyperplasia. No more advanced lesions were seen.
摘要
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