Pogodin M A
Fiziol Zh SSSR Im I M Sechenova. 1976 Jul;62(7):1013-8.
In 5 healthy young subjects, the intrathoracic pressure, pneumotachogram, and CO2 tension in exhaled air were recorded--under conditions of breathing with additional resistance (15 cm water/1/sec). While breathing with air, starting from the 1st respiratory cycle after switching on of the additional resistance, a respiratory regimen had been formed (decreased ventilation and increased respiratory activity) which did not alter during next 10 min. When breathing with hypercapnic mixture (4% CO2 in air), the respiratory regimen changed in two stages: a stepwise increase of respiratory activity and reducing of ventilation, and further gradual increase of these parameters. Increase in the respiratory activity was invariably followed by an increase in the CO2 alveolar tension. Role of chemo- and mechanoreceptors in formation of the ventilatory apparatus response to additional resistance against breathing, is discussed.
在5名健康年轻受试者中，记录了胸腔内压力、呼吸速度描记图和呼出气体中的二氧化碳张力——在附加阻力（15厘米水柱/升/秒）的呼吸条件下。在呼吸空气时，从开启附加阻力后的第1个呼吸周期开始，就形成了一种呼吸模式（通气减少和呼吸活动增加），在接下来的10分钟内没有改变。当呼吸高碳酸混合气（空气中4%二氧化碳）时，呼吸模式分两个阶段变化：呼吸活动逐步增加和通气减少，以及这些参数进一步逐渐增加。呼吸活动增加总是伴随着肺泡二氧化碳张力增加。讨论了化学感受器和机械感受器在形成呼吸对附加呼吸阻力的通气装置反应中的作用。
