光化学疗法的机制。
The mechanism of photochemotherapy.
作者信息
Gmeiner B, Raab W
出版信息
Dermatologica. 1976;152(5):281-5. doi: 10.1159/000251270.
PMID:955227
Abstract
As a contribution to the mechanisms of photochemotherapy, human skin homogenates were irradiated in the presence or absence of methoxsalen. The changes induced in LDH-, G-6-PDH-, GAPDH-, and GOT-activities were registered. Methoxsalen (50 mug/ml) failed to produce any significant effect. On pure G-6-PDH, methoxsalen exhibited a photoprotective action.
摘要
作为对光化学疗法机制的一项研究，在有或没有甲氧沙林存在的情况下对人皮肤匀浆进行照射。记录了乳酸脱氢酶（LDH）、葡萄糖-6-磷酸脱氢酶（G-6-PDH）、甘油醛-3-磷酸脱氢酶（GAPDH）和谷草转氨酶（GOT）活性的变化。甲氧沙林（50微克/毫升）未产生任何显著影响。对于纯的G-6-PDH，甲氧沙林表现出光保护作用。
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