Pulimood B M, Knudsen A, Coghill N F
Gut. 1976 Jun;17(6):463-70. doi: 10.1136/gut.17.6.463.
A partial gastrectomy of Billroth I or II type was performed in a series of 146 patients with peptic ulcer. Gastric biopsy was carried out two years later and the histology of the specimens compared with that of the body mucosa at the time of operation. In 138 patients without body atrophic gastritis (AG) before operation this condition was found in 74 (54%) two years after (46% of DU patients and 73% of GU patients). Those with antral or pyloric canal ulcers were particularly liable to develop AG (81%). Apart from site of ulcer various other factors possibly associated with the development of AG were examined: no positive correlations were found with the possible exception of anaemia. Gastric parietal cell antibodies were not found in any patient with AG tested. The cause of gastritis after partial gastrectomy and its possible relationship with gastric carcinoma are discussed.
对146例消化性溃疡患者进行了毕罗Ⅰ式或Ⅱ式部分胃切除术。两年后进行胃活检，并将标本的组织学与手术时胃体黏膜的组织学进行比较。在138例术前无胃体萎缩性胃炎（AG）的患者中，两年后有74例（54%）出现了这种情况（十二指肠溃疡患者中为46%，胃溃疡患者中为73%）。胃窦或幽门管溃疡患者尤其容易发生AG（81%）。除溃疡部位外，还检查了可能与AG发生相关的其他各种因素：除贫血可能存在相关性外，未发现其他正相关。在接受检测的任何AG患者中均未发现胃壁细胞抗体。讨论了部分胃切除术后胃炎的病因及其与胃癌的可能关系。
