Sipponen P, Hakkiluoto A, Kalima T V, Siurala M
Scand J Gastroenterol. 1976;11(8):813-6.
The mucosa of the gastric remnant of 41 subjects who had been operated upon 17-18 years earlier for peptic ulcer was studied histologically. The histological changes were classified as follows: 1) normal mucosa, 1; 2) simple gastritis, superficial or atrophic, 27; and 3) "selective loss of parietal cells", 13 subjects. The latter type was characterized by marked loss of parietal cells without corresponding loss of other epithelial elements and without an inflammatory reaction. These changes were thought to reflect a lack of a trophic action on parietal cells exerted by gastrointestinal hormones, as e.g. gastrins.
对41名17 - 18年前因消化性溃疡接受手术的受试者胃残余黏膜进行了组织学研究。组织学变化分类如下：1）正常黏膜，1例；2）单纯性胃炎，浅表性或萎缩性，27例；3）“壁细胞选择性缺失”，13例。后一种类型的特征是壁细胞明显缺失，而其他上皮成分无相应缺失且无炎症反应。这些变化被认为反映了胃肠激素如胃泌素对壁细胞缺乏营养作用。
