Stalenhoef A F
Afd. Algemeen Interne Geneeskunde, Academisch Ziekenhuis, Nijmegen.
Ned Tijdschr Geneeskd. 1997 Dec 27;141(52):2545-8.
Cholesterol synthesis (HMG-CoA reductase) inhibitors have proven their value in preventing cardiovascular events, especially in patients with manifest coronary heart disease. Besides cholesterol lowering a number of effects have been described which may contribute to the beneficial influence of these agents on the process of atherosclerosis. Measurement of serum lipids is still necessary for various reasons, namely, to know the degree of elevation in serum cholesterol and specific disturbances in lipid metabolism, the extent to which serum lipids must be lowered and the compliance with cholesterol lowering therapy.
胆固醇合成（HMG-CoA还原酶）抑制剂已在预防心血管事件方面证明了其价值，尤其是在患有明显冠心病的患者中。除了降低胆固醇外，还描述了许多可能有助于这些药物对动脉粥样硬化进程产生有益影响的作用。由于各种原因，血清脂质的测量仍然是必要的，即了解血清胆固醇的升高程度和脂质代谢的特定紊乱情况、血清脂质必须降低的程度以及对降胆固醇治疗的依从性。
