短杆菌肽A单体-二聚体状态的光散射研究。
Light-scattering studies of the monomer-dimer states of gramicidin A.
作者信息
Rondelez F, Litster J D
出版信息
Biophys J. 1979 Sep;27(3):455-60. doi: 10.1016/S0006-3495(79)85229-7.
Abstract
Measurements of the intensity and autocorrelation function of ligh quasielastically scattered by gramicidin A indicate that the molecules exist as dimers in methanol and dioxane and monomers in dimethyl sulfoxide when solute concentrations range from 18 to 50 mg/ml. This gives further evidence that gramicidin A can dimerize in low-polarity media such as the hydrocarbon part of the membrane bilayers.
摘要
短杆菌肽A准弹性散射光的强度和自相关函数测量表明，当溶质浓度在18至50毫克/毫升范围内时，该分子在甲醇和二恶烷中以二聚体形式存在，而在二甲基亚砜中以单体形式存在。这进一步证明短杆菌肽A能够在低极性介质（如膜双层的烃类部分）中形成二聚体。
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本文引用的文献
1
GRAMICIDIN A. V. THE STRUCTURE OF VALINE- AND ISOLEUCINE-GRAMICIDIN A.短杆菌肽A。五、缬氨酸 - 和异亮氨酸 - 短杆菌肽A的结构
J Am Chem Soc. 1965 May 5;87:2011-20. doi: 10.1021/ja01087a027.
2
Development of K+-Na+ discrimination in experimental bimolecular lipid membranes by macrocyclic antibiotics.大环抗生素对实验性双分子脂质膜中钾离子 - 钠离子选择性的影响
Biochem Biophys Res Commun. 1967 Feb 21;26(4):398-404. doi: 10.1016/0006-291x(67)90559-1.
3
Effects associated with permeability changes caused by gramicidin A in electroplax membrane.
Nature. 1969 Feb 8;221(5180):541-5. doi: 10.1038/221541a0.
4
The gramicidin A transmembrane channel: characteristics of head-to-head dimerized (L,D) helices.短杆菌肽A跨膜通道：头对头二聚化（L，D）螺旋的特征
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1907-11. doi: 10.1073/pnas.68.8.1907.
5
The gramicidin A transmembrane channel: a proposed pi(L,D) helix.短杆菌肽A跨膜通道：一种推测的π（L，D）螺旋
Proc Natl Acad Sci U S A. 1971 Mar;68(3):672-6. doi: 10.1073/pnas.68.3.672.
6
Observation of the spectrum of light scattered by solutions of biological macromolecules.生物大分子溶液散射光光谱的观察
Proc Natl Acad Sci U S A. 1967 May;57(5):1164-71. doi: 10.1073/pnas.57.5.1164.
7
Spectroscopic studies on the conformation of gramicidin A'. Proton magnetic resonance assignments, coupling constants, and H-D exchange.短杆菌肽A构象的光谱研究。质子磁共振归属、耦合常数及H-D交换
Biochemistry. 1972 Feb 15;11(4):477-86. doi: 10.1021/bi00754a001.
8
The aggregation of gramicidin A in solution.短杆菌肽A在溶液中的聚集。
Biochemistry. 1974 Dec 17;13(26):5257-64. doi: 10.1021/bi00723a002.
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10
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