Cherukupally S R, Merchant S N, Rosowski J J
Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
Ann Otol Rhinol Laryngol. 1998 Apr;107(4):319-26. doi: 10.1177/000348949810700410.
The goal of this temporal bone study was to quantify the relationship between specific histologic changes at the stapes footplate and the magnitude of the air-bone gap in otosclerosis. The study material comprised 26 specimens with otosclerosis and 37 age-matched controls. Detailed anatomic measurements were made on each histologic section through the stapes footplate in each bone, resulting in 30 different measurement parameters for each bone. For frequencies 250 to 2,000 Hz, the conductive hearing loss correlated highly with (p < .01) and appeared to be caused primarily by narrowing and loss of the annular ligament, especially at the posterior stapediovestibular joint space. The size of the air-bone gap appeared to be determined by the extent and degree of this pathologic change. Schuknecht's hypothesis that bony ankylosis of the footplate would be associated with an air-bone gap of >30 dB was supported by our data. However, the degree and extent of bony footplate ankylosis could not be reliably predicted by the size of the air-bone gap.
这项颞骨研究的目的是量化耳硬化症中镫骨足板特定组织学变化与气骨导间距大小之间的关系。研究材料包括26例耳硬化症标本和37例年龄匹配的对照。对每块骨中穿过镫骨足板的每个组织学切片进行详细的解剖测量，每块骨产生30个不同的测量参数。对于250至2000赫兹的频率，传导性听力损失与之高度相关（p <.01），并且似乎主要是由环状韧带变窄和缺失引起的，尤其是在镫骨前庭后关节间隙处。气骨导间距的大小似乎由这种病理变化的范围和程度决定。我们的数据支持了舒克内希特的假设，即足板骨融合会与大于30分贝的气骨导间距相关。然而，气骨导间距的大小无法可靠地预测足板骨融合的程度和范围。
