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使用可吸收膜引导组织再生治疗牙龈退缩型缺损:一项人体组织学病例报告

Guided tissue regeneration using a resorbable membrane in gingival recession-type defects: a histologic case report in humans.

作者信息

Vincenzi G, De Chiesa A, Trisi P

机构信息

Biomaterials Clinical Research Association, Pescara, Italy.

出版信息

Int J Periodontics Restorative Dent. 1998 Feb;18(1):24-33.

PMID:9558554
Abstract

This case report clinically and histologically evaluated the regeneration of gingival tissues with the use of resorbable membranes. The study was performed on a premolar for which extraction was planned. The exposed root surface was thoroughly cleaned and planed with curettes and rotary instruments, and two notches were created on the facial aspect of the exposed root surface. A resorbable Resolute membrane (WL Gore) was applied above the defect to allow for gingival regeneration. After a 6-month healing period, a block section containing the root and the regenerated tissues was removed. The biopsy specimen was processed to obtain thin ground sections. The histologic analysis demonstrated the formation of a newly generated periodontal tissue from the deepest notch toward the coronal gingiva. The newly formed tissue was composed of a coronal area of connective tissue attachment and an apical area of bone fibers and cementum. The present report histologically demonstrates the ability of a resorbable membrane to allow complete regeneration of the periodontal ligament in the coverage of gingival recessions.

摘要

本病例报告从临床和组织学角度评估了使用可吸收膜再生牙龈组织的情况。该研究在一颗计划拔除的前磨牙上进行。用刮治器和旋转器械彻底清洁并平整暴露的牙根表面,并在暴露牙根表面的颊侧制造两个切口。在缺损上方应用可吸收的Resolute膜(WL Gore)以促进牙龈再生。经过6个月的愈合期后,切除包含牙根和再生组织的块状切片。对活检标本进行处理以获得薄磨片。组织学分析表明,从最深的切口向冠方牙龈形成了新生成的牙周组织。新形成的组织由结缔组织附着的冠方区域和骨纤维及牙骨质的根方区域组成。本报告从组织学角度证明了可吸收膜在覆盖牙龈退缩时能够使牙周韧带完全再生。

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引用本文的文献

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A new modified bone grafting technique for periodontally accelerated osteogenic orthodontics.一种用于牙周加速成骨正畸的新型改良骨移植技术。
Medicine (Baltimore). 2018 Sep;97(37):e12047. doi: 10.1097/MD.0000000000012047.
2
Formation of human cementum following different modalities of regenerative therapy.不同再生治疗方式后人类牙骨质的形成
Clin Oral Investig. 2005 Mar;9(1):58-64. doi: 10.1007/s00784-004-0288-x. Epub 2005 Jan 6.