Muntean W, Müller W D
Helv Paediatr Acta. 1976 Aug;31(2):149-58.
Coagulation studies from capillary blood, consisting of the determination of fibrinogen, factors II and V and proactivator-plasminogen, were done in 104 newborns. In healthy newborns fibrinogen and factor V was found near the adult level, while factor II and proactivator-plasminogen showed a severe deficit. None of the coagulation factors was dependent of gestational age. Fibrinogen was significantly lower in the group of children with perinatal asphyxia. In ill newborns there was a significant correlation between fibrinogen and factor II and fibrinogen and factor V as was between factors II and V. No correlation could be demonstrated between proactivator-plasminogen and any of the other coagulation factors.
对104例新生儿进行了毛细血管血凝血研究,包括纤维蛋白原、凝血因子II和V以及前激活物-纤溶酶原的测定。在健康新生儿中,发现纤维蛋白原和凝血因子V接近成人水平,而凝血因子II和前激活物-纤溶酶原严重缺乏。没有一种凝血因子依赖于胎龄。围产期窒息患儿组的纤维蛋白原明显较低。在患病新生儿中,纤维蛋白原与凝血因子II、纤维蛋白原与凝血因子V之间以及凝血因子II与V之间存在显著相关性。前激活物-纤溶酶原与任何其他凝血因子之间均未显示出相关性。