Lee M S, Gonzalez C
Department of Ophthalmology, Yale University, New Haven, CT 06520, USA.
Am J Ophthalmol. 1998 Apr;125(4):554-6. doi: 10.1016/s0002-9394(99)80199-8.
To describe the association of unilateral peripapillary myelinated retinal nerve fibers with myopia, strabismus, and amblyopia and to propose a possible pathologic mechanism.
Four patients who have the findings associated with unilateral peripapillary myelinated nerve fibers are described and reviewed.
All patients had poor visual outcomes despite treatment with full cycloplegic refraction and appropriate patching.
Although the origin of this association is unknown, we believe that peripapillary myelinated nerve fibers in a unilateral myopic eye may be secondary to an imbalance between the process of myelination and the formation of the lamina cribrosa. Good results have been reported with amblyopic therapy; however, it is our experience that these patients are somewhat refractory to amblyopia therapy.
描述单侧视乳头周围有髓神经纤维与近视、斜视及弱视之间的关联，并提出一种可能的病理机制。
描述并回顾了4例有单侧视乳头周围有髓神经纤维相关表现的患者。
尽管进行了充分的睫状肌麻痹验光和适当的遮盖治疗，所有患者的视力预后均较差。
虽然这种关联的起源尚不清楚，但我们认为单侧近视眼中的视乳头周围有髓神经纤维可能继发于髓鞘形成过程与筛板形成之间的失衡。弱视治疗已报道有良好效果；然而，根据我们的经验，这些患者对弱视治疗 somewhat refractory（此处原文有误，refractory意为“难治的”，结合语境推测可能是“这些患者对弱视治疗有些难治” ）。
