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儿童皮肤结节性多动脉炎及文献综述

Cutaneous polyarteritis nodosa in a child and a review of the literature.

作者信息

Mocan H, Mocan M C, Peru H, Ozoran Y

机构信息

Department of Paediatrics, Faculty of Medicine, Karadeniz (Black Sea) Technical University, Trabzon, Turkey.

出版信息

Acta Paediatr. 1998 Mar;87(3):351-3. doi: 10.1080/08035259850157471.

Abstract

The cutaneous form of polyarteritis nodosa in children is extremely rare. Findings are usually limited to the skin, muscles and joints. It has a benign but often chronic course. We describe an 8-y-old girl with cutaneous PAN, with extensive livedo reticularis on lower and upper extremities, tender subcutaneous nodules, arthralgia and right ankle swelling. Skin biopsy revealed vasculitis of small and medium-sized blood vessels characterized by fibrinoid necrosis. The use of prednisolone resulted in clinical improvement initially, but recurrence occurred during tapering. She showed marked improvement with additional high dose methyl prednisolone monthly.

摘要

儿童结节性多动脉炎的皮肤型极为罕见。症状通常局限于皮肤、肌肉和关节。病程呈良性,但往往为慢性。我们描述了一名8岁患有皮肤型结节性多动脉炎的女孩,其上下肢有广泛的网状青斑、压痛性皮下结节、关节痛和右踝肿胀。皮肤活检显示中小血管血管炎,其特征为纤维蛋白样坏死。使用泼尼松龙最初使临床症状有所改善,但在减量过程中复发。每月额外给予大剂量甲泼尼龙后,她的症状有了显著改善。

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