Kusama N, Mabuchi N, Katsuya H, Fujita Y, Hatta M
Department of Anesthesiology & Resuscitology, Nagoya City University Medical School.
Masui. 1998 Mar;47(3):310-3.
Microlaryngeal surgery was performed with total intravenous anesthesia using pentazocine and propofol in 20 patients. The patients were paralyzed by suxamethonium infusion and ventilated by high frequency jet ventilation via the laryngoscope. In place of the opioid analgesics commonly used in TIVA for microlaryngeal surgery, pentazocine was given. All but one of the patients received pentazocine 15 m.g. intramuscularly as a premedication and then another 15 m.g. intravenously for induction of anesthesia. Average time of surgeries was 33.6 minutes. Average doses of pentazocine and suxamethonium given during surgeries were 369 m.g. and 286 m.g., respectively. This technique allowed stable anesthesia to be achieved with rapid postoperative recovery, without serious complications like intraoperative return of awareness.
对20例患者采用喷他佐辛和丙泊酚进行全静脉麻醉实施显微喉镜手术。患者通过输注琥珀胆碱使其肌肉松弛，并经喉镜进行高频喷射通气。在显微喉镜手术的全静脉麻醉中，使用喷他佐辛替代了常用的阿片类镇痛药。除1例患者外，所有患者术前肌肉注射喷他佐辛15毫克作为术前用药，然后静脉注射另外15毫克用于麻醉诱导。手术平均时间为33.6分钟。手术期间喷他佐辛和琥珀胆碱的平均剂量分别为369毫克和286毫克。该技术可实现稳定的麻醉，术后恢复迅速，且无术中苏醒等严重并发症。
