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[通过光致变色成像对人工心脏瓣膜的流体动力学特性进行研究]

[Study of hydrodynamic characteristics of artificial heart valves by photochromic imaging].

作者信息

Vil'danov L M, Etonov M P, Iurechko V N

出版信息

Med Tekh. 1998 Jan-Feb(1):10-20.

PMID:9560812
Abstract

The paper deals with the hydrodynamics of artificial heart valves (AHVs) used in clinical practice. It reviews and analyzes the studies of AHV hydrodynamics, as well as the hydrodynamic beds which stimulate physiological flow through the valve. Photochronic imaging (PCI) is proposed for examination of AHV hydrodynamic characteristics under model physiological flow. The hydrodynamics of different AHVs was tested on the beds simulating blood flow through AHVs by employing PCI. PCI involved preparation of model photochronic solution that simulates blood, colour labels by using laser radiation. In the model photochronic solution, 10(-6)-10(-9)-sec laser radiation gave rise to linear colour labels whose movement was recorded by a speed camera in the flow behind the valve. The profiles of speed behind the valves, the dimensions of congestive areas, the positions of flow detachment and regurgitation flow were calculated by a speed shooting in different periods of valvular performance. PCI defined congestive areas behind the valves, the areas of closed circulations, the sizes of reversing flow areas and examined the time course of flow behind the valves as a whole. The paper is of interest for AHV designers and cardiac surgeons who apply various AHVs.

摘要

本文探讨了临床实践中使用的人工心脏瓣膜(AHV)的流体动力学。它回顾并分析了AHV流体动力学的研究,以及模拟通过瓣膜的生理血流的流体动力学试验台。提出了光时成像(PCI)用于在模拟生理血流条件下检测AHV的流体动力学特性。通过PCI在模拟血液流经AHV的试验台上测试了不同AHV的流体动力学。PCI包括制备模拟血液的光时模型溶液,利用激光辐射进行颜色标记。在光时模型溶液中,10^(-6)-10^(-9)秒的激光辐射产生线性颜色标记,其运动由阀门后方流场中的高速摄像机记录。通过在瓣膜工作的不同时期进行高速拍摄,计算阀门后方的速度分布、充血区域的尺寸、血流分离和反流的位置。PCI确定了阀门后方的充血区域、封闭循环区域、反流区域的大小,并整体研究了阀门后方血流随时间的变化过程。本文对于使用各种AHV的AHV设计者和心脏外科医生具有参考价值。

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