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[胎儿组织在耳鼻咽喉科的移植:现状与未来展望]

[Transplantation of fetal tissues in otorhinolaryngology: current status and prospects for the future].

作者信息

Magomedov M M

出版信息

Vestn Otorinolaringol. 1998(2):16-23.

PMID:9560977
Abstract

Insufficient efficacy of treatment of neurosensory hypoacusis makes investigators search for new methods. Transplantation of fetal tissue taken from healthy embryos of gestation stage II tried in various fields of medicine, such as neurology, endocrinology, surgery, etc., was also tested in management of various forms of neurosensory hypoacusis. Endonasal, endaural, endolumbal and intracochlear methods of the transplantation are detailed. Results of combined dynamic audiological control of these patients including tonal threshold audiometry in extended frequency range are presented. A 1-year follow-up provided evidence in favour of endolumbal and intracochlear transplantation. Further investigations are needed.

摘要

神经感觉性听力减退的治疗效果不佳促使研究人员寻找新的方法。取自妊娠II期健康胚胎的胎儿组织移植已在医学的各个领域进行尝试,如神经学、内分泌学、外科手术等,也被用于治疗各种形式的神经感觉性听力减退。详细介绍了经鼻、经耳、经腰和经耳蜗的移植方法。展示了对这些患者进行联合动态听力学控制的结果,包括扩展频率范围内的纯音阈值测听。1年的随访结果支持经腰和经耳蜗移植。还需要进一步的研究。

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