Izquierdo J A, Rabiller G, Costas S M, Justel E A, Savini C V
Acta Physiol Lat Am. 1979;29(4-5):239-43.
Female Wistar rats when crowded together become aggressive if fed a diet with low tryptophan (Trp) content (maize, flour, Mf). When isolated during 30 days and fed Mf they show a decrease of weight, of total plasma Trp, and of Trp and 5-hydroxytryptamine (5-HT) in brain stem, but 5-hydroxyindolacetic acid (5-HIAA) of the same cerebral area does not change. These results partially agree with other authors observations. Mice isolated during 47 days and fed with Mf do not show any significant weight variation, the hypermotility of isolated mice on normal diet persists, but 5-HT and 5-HIAA significantly decreases in total brain, an effect that has been observed by another author. The effect on 5-HIAA does not depend on the diet, either balanced or with low Trp content.
雌性Wistar大鼠如果喂食色氨酸（Trp）含量低的饮食（玉米、面粉，Mf），当拥挤在一起时会变得具有攻击性。当在30天内隔离并喂食Mf时，它们的体重、血浆总色氨酸、脑干中的色氨酸和5-羟色胺（5-HT）会减少，但同一脑区的5-羟吲哚乙酸（5-HIAA）没有变化。这些结果与其他作者的观察结果部分一致。在47天内隔离并喂食Mf的小鼠没有表现出任何显著的体重变化，正常饮食的隔离小鼠的多动仍然存在，但全脑中5-HT和5-HIAA显著降低，这一效应已被另一位作者观察到。对5-HIAA的影响不取决于饮食，无论是均衡饮食还是色氨酸含量低的饮食。
