Karel I, Kalvodová B, Kuthan P
Second Department of Ophthalmology, General Faculty Hospital, 1st Medical Faculty, Charles University, Prague, Czech Republic.
Graefes Arch Clin Exp Ophthalmol. 1998 Apr;236(4):255-8. doi: 10.1007/s004170050073.
To evaluate the results of penetrating keratoplasty (PK) in bullous silicone oil keratopathy (BSK).
PK for BSK was performed in 13 patients, aged from 31 to 82 years. In all patients, pars plana vitrectomy (PPV) with silicone oil implantation (SOI) had been previously performed as the definitive surgery: for complicated retinal detachment with advanced proliferative vitreoretinopathy in 12 eyes and for diabetic traction detachment in one eye. Seven patients were monocular. All 13 eyes were aphakic and there was a long-lasting contact of silicone oil with the corneal endothelium. Before keratoplasty, each eye underwent between two and five operations, on average three, for retinal detachment or late complications of SOI. The interval between SOI and PK was from 11 to 79 months. The patients were followed up for 12-52 months.
At the last follow-up examination, a clear graft was found in 6 out of 13 eyes (46%). The six clear grafts were found in the ten eyes where silicone oil had been removed before keratoplasty. The graft became opaque in all three eyes in which silicone oil had not been removed. Six out of seven eyes with failed grafts atrophied. Visual acuity improved in all six eyes with the clear graft from had movement preoperatively to 0.05-0.25. The decreased visual acuity was caused by irreparable damage to the macula, which resulted from high myopia, proliferative vitreoretinopathy or long-lasting detachment of the macula.
PK in BSK was successful only in those eyes in which the attached retina enabled the removal of the silicone oil before the PK. The reattached retina and useful visual acuity before the development of BSK were the preconditions for functional success of the PK.
评估穿透性角膜移植术(PK)治疗大泡性硅油角膜病变(BSK)的效果。
对13例年龄在31至82岁之间的患者实施了针对BSK的PK手术。所有患者此前均已接受过玻璃体切除术(PPV)并植入硅油(SOI)作为确定性手术:12眼用于治疗伴有晚期增生性玻璃体视网膜病变的复杂性视网膜脱离,1眼用于治疗糖尿病性牵拉性视网膜脱离。7例患者为单眼患病。所有13只眼均为无晶状体眼,且硅油与角膜内皮存在长期接触。在角膜移植术前,每只眼平均接受了2至5次手术(平均3次),用于治疗视网膜脱离或SOI的晚期并发症。SOI与PK之间的间隔时间为11至79个月。对患者进行了12至52个月的随访。
在最后一次随访检查时,13只眼中有6只(46%)移植片保持透明。这6片透明移植片出现在角膜移植术前已取出硅油的10只眼中。在未取出硅油的3只眼中,移植片均变混浊。7只移植失败的眼中有6只发生萎缩。6只移植片透明的眼视力均有提高,从术前仅能感知光移动提高到了0.05至0.25。视力下降是由于高度近视、增生性玻璃体视网膜病变或黄斑长期脱离导致黄斑受到不可修复的损害。
只有在视网膜复位且能够在PK术前取出硅油的眼中,PK治疗BSK才会成功。视网膜复位以及在BSK发生前具有有用视力是PK获得功能成功的前提条件。