Tran D B, Silverman S E, Zimmerman K, Feldon S E
Department of Ophthalmology, University of Southern California, Los Angeles, California, USA.
Graefes Arch Clin Exp Ophthalmol. 1998 Apr;236(4):269-73. doi: 10.1007/s004170050076.
The purpose of this study was to evaluate the effect of aging on motion detection and perception.
Forty-six subjects, ages 19-92 years, were asked to view a motion stimulus. Infrared oculography was used to objectively evaluate motion detection by documenting the presence of optokinetic nystagmus as the subjects viewed the stimulus. Subjective responses to motion perception were recorded using a computer joystick.
Optokinetic nystagmus was clearly detectable in all 46 subjects. Motion detection and perception thresholds showed age-related deterioration. No relationship was found to gender or age-gender interaction.
The results indicate motion detection and perception thresholds deteriorate with age. This may reflect a susceptibility to age-related degeneration in specific cortical areas responsible for motion perception as well as neurodegeneration in the retinogeniculate pathway.
本研究旨在评估衰老对运动检测和感知的影响。
46名年龄在19至92岁之间的受试者被要求观看运动刺激。通过记录受试者观看刺激时视动性眼球震颤的存在，使用红外眼动图客观评估运动检测。使用计算机操纵杆记录对运动感知的主观反应。
所有46名受试者均能清晰检测到视动性眼球震颤。运动检测和感知阈值显示出与年龄相关的恶化。未发现与性别或年龄-性别相互作用有关。
结果表明运动检测和感知阈值随年龄增长而恶化。这可能反映了负责运动感知的特定皮质区域对与年龄相关的退化以及视网膜膝状体通路中的神经退行性变的易感性。
