Hess C, Steiger J U, Schifferli J A
Department of Forschung, Kantonsspital Basel, Basel.
Schweiz Med Wochenschr. 1998 Mar 14;128(11):393-9.
The complement system as a part of innate immunity is considered to provide rapid tough incomplete antimicrobial activity. However, besides providing a first-line defence, innate immunity plays additional important roles: it initiates and improves the slower, but more specific, acquired immune response. The recognition and destruction of noxious substances, as well as initiation of the acquired immune response, are accompanied by potentially hazardous inflammation. The inflammatory process has thus to be tightly regulated. In this overview, innate immunity and its interactions with acquired immunity are discussed with the main focus on the complement system. Our scientific interests are integrated into the discussion on complement.
补体系统作为固有免疫的一部分，被认为可提供快速但不完整的抗菌活性。然而，除了提供一线防御外，固有免疫还发挥着其他重要作用：它启动并增强较慢但更具特异性的获得性免疫反应。对有害物质的识别和破坏以及获得性免疫反应的启动都伴随着潜在危险的炎症。因此，炎症过程必须受到严格调控。在本综述中，将讨论固有免疫及其与获得性免疫的相互作用，主要重点是补体系统。我们的科学兴趣融入了关于补体的讨论中。
