Korpelainen E I, Alitalo K
Molecular/Cancer Biology Laboratory, Haartman Institute, University of Helsinki, Finland.
Curr Opin Cell Biol. 1998 Apr;10(2):159-64. doi: 10.1016/s0955-0674(98)80137-3.
Exciting progress has been made in elucidating the complex network of receptor-ligand interactions that regulate blood vessel growth. Understanding these control mechanisms is of interest not only because of their role in developmental biology, but because they provide potential therapeutic strategies for disease processes involving angiogenesis, such as tumor growth.
在阐明调节血管生长的受体 - 配体相互作用复杂网络方面已取得了令人兴奋的进展。了解这些控制机制不仅因其在发育生物学中的作用而备受关注,还因为它们为涉及血管生成的疾病过程(如肿瘤生长)提供了潜在的治疗策略。