Imperadore F, Basso C, Thiene G
Divisione di Cardiologia, Ospedale Civile, Rovereto TN.
G Ital Cardiol. 1998 Mar;28(3):297-302.
A 32-year-old man without risk factors for coronary artery disease but moderate cigarette smoking died suddenly 5 years after a cardiological check-up for chest pain on effort. Autopsy investigation ruled out extracardiac causes of death and pointed to a multivessel coronary artery disease with organized and recanalized occlusive thrombosis, sometimes superimposed to smooth muscle cells proliferation, in the absence of peripheral vascular disease. Thromboangiitis obliterans of the coronary arteries or accelerated atherosclerosis complicated by thrombosis due to endothelial erosion are debated as possible etiopathogenetic mechanisms. The case is still open for achieving a final diagnosis.
一名32岁男性,无冠状动脉疾病危险因素,但有中度吸烟史,在因劳力性胸痛接受心脏检查5年后突然死亡。尸检排除了心外原因导致的死亡,并指出存在多支冠状动脉疾病,伴有机化和再通的闭塞性血栓形成,有时叠加平滑肌细胞增殖,且无周围血管疾病。冠状动脉血栓闭塞性脉管炎或因内皮糜烂导致血栓形成并发的加速动脉粥样硬化被认为是可能的发病机制。该病例仍有待最终确诊。