Olney R K
Department of Neurology, University of California, San Francisco 94143-0114, USA.
Semin Neurol. 1998;18(1):63-72. doi: 10.1055/s-2008-1040862.
Neuropathies are a common neurologic manifestation of diffuse connective tissue disease. Vasculitic neuropathy requires prompt diagnosis and treatment to improve its outcome. It is commonly multifocal but may be confluent and symmetrical. Vasculitic neuropathy needs to be distinguished from the more common syndromes of compression neuropathy, which may also be multifocal, and nonvasculitic distal axonal polyneuropathy. Sensory neuronopathy is a distinctive syndrome unique to Sjögren's syndrome among the connective tissue diseases. Trigeminal sensory neuropathy may be the presenting feature of systemic sclerosis or may develop during the course of other connective tissue diseases. This article reviews the clinical and diagnostic features of neuropathies associated with the common diffuse connective tissue diseases.
神经病变是弥漫性结缔组织病常见的神经表现。血管炎性神经病变需要及时诊断和治疗以改善预后。它通常为多灶性，但也可能融合且对称。血管炎性神经病变需要与更常见的压迫性神经病变综合征（也可能是多灶性）以及非血管炎性远端轴索性多发性神经病变相鉴别。感觉神经元病是结缔组织病中干燥综合征特有的一种独特综合征。三叉神经感觉神经病变可能是系统性硬化症的首发特征，也可能在其他结缔组织病病程中出现。本文综述了与常见弥漫性结缔组织病相关的神经病变的临床和诊断特征。
