Nambirajan L, Rintala R J, Losty P D, Carty H, Lloyd D A
Department of Paediatric Surgery, Alder Hey Children's Hospital, Liverpool, UK.
Pediatr Surg Int. 1998 Mar;13(2-3):76-8. doi: 10.1007/s003830050252.
The aim of the study was to examine the relationship between anastomotic leaks and the development of symptomatic anastomotic strictures after primary repair of oesophageal atresia (OA) with or without tracheo-oesophageal fistula (TOF) and the prognostic value of the anastomotic appearance on postoperative oesophagography. The records and X-ray films of 49 patients with OA with or without TOF admitted between January 1990 and June 1995 were reviewed retrospectively. Of these, 37 had a primary repair (34 immediate and 3 delayed) and a postoperative contrast swallow was done between day 5 and day 30 (median day 7). Radiological leaks were documented. In addition, the maximum transverse diameters of the upper pouch and anastomotic region and the length of the anastomotic narrow segment were measured; the ratio of upper-pouch diameter to that of the anastomosis was calculated (anastomotic index, AI). The need for dilatation of symptomatic anastomotic strictures and for repeat dilatation as a separate episode were documented. Of the 37 patients, 4 developed an anastomotic leak (11%), 3 radiological and 1 clinical. A symptomatic stricture occurred in 55% of patients. There was no correlation between a leak and later development of a symptomatic stricture, although the small number of patients with leaks precluded definite conclusions. No radiological leak progressed to a clinical leak. There was no correlation between the AI or the length of the anastomotic narrow segment and the need for dilatation, the need for repeat dilatation, or the number of dilatations. In this study, the presence of a leak, the AI, and the length of the narrow segment on early postoperative contrast swallow did not correlate with the later development of a symptomatic stricture. A radiological leak was of no clinical significance. Since major leaks are apparent clinically, an early routine contrast study did not influence management and is not necessary.
本研究旨在探讨食管闭锁(OA)伴或不伴气管食管瘘(TOF)一期修复术后吻合口漏与症状性吻合口狭窄发生之间的关系,以及术后食管造影时吻合口表现的预后价值。回顾性分析了1990年1月至1995年6月收治的49例伴或不伴TOF的OA患者的病历和X线片。其中37例行一期修复(34例即刻修复,3例延迟修复),术后第5天至第30天(中位时间为第7天)进行了吞咽造影检查。记录了放射学上的吻合口漏情况。此外,测量了上袋和吻合口区的最大横径以及吻合口狭窄段的长度;计算上袋直径与吻合口直径的比值(吻合口指数,AI)。记录了症状性吻合口狭窄扩张的必要性以及作为单独一次的重复扩张情况。37例患者中,4例发生吻合口漏(11%),3例为放射学漏,1例为临床漏。55%的患者出现症状性狭窄。虽然吻合口漏与症状性狭窄的后期发生之间无相关性,但漏诊患者数量较少,无法得出明确结论。没有放射学漏进展为临床漏。AI或吻合口狭窄段长度与扩张必要性、重复扩张必要性或扩张次数之间无相关性。在本研究中,术后早期吞咽造影时吻合口漏的存在、AI以及狭窄段长度与症状性狭窄的后期发生无关。放射学漏无临床意义。由于严重漏在临床上很明显,早期常规造影检查不影响治疗,且没有必要。