Gschwend J E, Hautmann R E
Urologische Universitätsklinik Ulm.
Urologe A. 1998 Mar;37(2):172-4. doi: 10.1007/s001200050170.
Gene transfer strategies for prostate cancer may yield promising future perspectives. In this regard, gene modified tumor vaccines, suicide gene therapy and gene replacement of nonfunctioning tumor suppressor genes are of special interest. Clinical phase I and early phase II studies with gene modified vaccines have to demonstrate the clinical implication of these new therapeutic options. Apart from this approach the development of more efficient delivery systems for in vivo gene transfer is highly desirable.
前列腺癌的基因转移策略可能会带来充满希望的未来前景。在这方面，基因修饰肿瘤疫苗、自杀基因疗法以及无功能肿瘤抑制基因的基因替代特别受关注。基因修饰疫苗的临床I期和早期II期研究必须证明这些新治疗选择的临床意义。除了这种方法外，非常需要开发更有效的体内基因转移递送系统。
