Cimmino M, Granström M, Gray J S, Guy E C, O'Connell S, Stanek G
Dipartimento di Medicina Interna, Universita degli Studi de Genova, Italy.
Zentralbl Bakteriol. 1998 Mar;287(3):248-52. doi: 10.1016/s0934-8840(98)80126-6.
At a series of meetings, involving 27 clinicians from 11 countries, case definitions for the diagnosis of Lyme borreliosis in Europe were agreed and are presented here, with appropriate serological criteria, as a diagnostic guide. In a separate study questionnaires directed to clinicians were used to collect information on clinical aspects and risk factors of Lyme borreliosis. Data on the number of Lyme borreliosis patients seen by physicians indicated a low prevalence of the disease in western Europe and a relatively high prevalence in eastern Europe. The most commonly encountered symptom was erythema migrans, followed by neurological manifestations. Cardiac problems were rare. Tick bite was strongly associated with Lyme borreliosis, but the only other significantly associated risk factor was the pastime of gardening.
在一系列会议上，来自11个国家的27名临床医生参与其中，会上商定了欧洲莱姆病诊断的病例定义，并在此列出，同时给出了适当的血清学标准，作为诊断指南。在另一项研究中，向临床医生发放问卷，以收集有关莱姆病临床症状和危险因素的信息。医生诊治的莱姆病患者数量数据表明，该病在西欧患病率较低，而在东欧相对较高。最常出现的症状是游走性红斑，其次是神经症状。心脏问题较为罕见。蜱虫叮咬与莱姆病密切相关，但唯一另一个显著相关的危险因素是园艺活动。
