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The cloning and characterization of a novel cytochrome P450 family, CYP26, with specificity toward retinoic acid.

作者信息

Haque M, Anreola F

机构信息

Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4255, USA.

出版信息

Nutr Rev. 1998 Mar;56(3):84-5. doi: 10.1111/j.1753-4887.1998.tb01699.x.

Abstract

A new family of cytochrome P450 enzymes, CYP26, has been cloned and characterized in zebra fish, human, and mouse tissues. CYP26 displays specificity toward retinoic acid and it may function as an important regulator or differentiation and a possible modulator of disease states by controlling retinoid concentration and homeostasis.

摘要

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