• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Identification of Nramp2 as an iron transport protein: another piece of the intestinal iron absorption puzzle.

作者信息

Fleet J C

机构信息

University of North Carolina, Greensboro 27412-5001, USA.

出版信息

Nutr Rev. 1998 Mar;56(3):88-9. doi: 10.1111/j.1753-4887.1998.tb01701.x.

DOI:10.1111/j.1753-4887.1998.tb01701.x
PMID:9564183
Abstract

Although a number of iron-binding proteins have been identified, the roles for specific proteins in mediating iron absorption have not been definitively assigned. Two recent papers report the identification of an iron transport protein that may be responsible for movement of iron from the intestinal lumen into the enterocyte. Coupled with the recent identification of the protein mutated in hemochromatosis, researchers are now establishing a clearer picture of the mechanism of intestinal iron absorption.

摘要

相似文献

1
Identification of Nramp2 as an iron transport protein: another piece of the intestinal iron absorption puzzle.
Nutr Rev. 1998 Mar;56(3):88-9. doi: 10.1111/j.1753-4887.1998.tb01701.x.
2
Recently identified molecular aspects of intestinal iron absorption.近期发现的肠道铁吸收的分子机制
J Nutr. 1998 Nov;128(11):1841-4. doi: 10.1093/jn/128.11.1841.
3
Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.Nramp2在贫血的贝尔格莱德(b)大鼠中发生突变:Nramp2在内体铁转运中起作用的证据。
Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1148-53. doi: 10.1073/pnas.95.3.1148.
4
Reciprocal regulation of HFE and NNamp2 gene expression by iron in human intestinal cells.铁对人肠道细胞中HFE和NNamp2基因表达的相互调节
J Nutr. 1999 Jan;129(1):98-104. doi: 10.1093/jn/129.1.98.
5
The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms.人类Nramp2基因:基因结构、可变剪接、启动子区域及多态性的特征分析
Blood Cells Mol Dis. 1998 Jun;24(2):199-215. doi: 10.1006/bcmd.1998.0186.
6
Iron absorption: relative importance of iron transport pathways.铁吸收:铁转运途径的相对重要性
Am J Hematol. 2001 Jul;67(3):215. doi: 10.1002/ajh.1114.
7
Iron absorption and transport.铁的吸收与转运。
Am J Med Sci. 1999 Oct;318(4):213-29. doi: 10.1097/00000441-199910000-00002.
8
Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells.Nramp2的表达与人类肠道Caco-2细胞顶膜上pH依赖的铁摄取有关。
J Biol Chem. 2000 Jan 14;275(2):1023-9. doi: 10.1074/jbc.275.2.1023.
9
[Intestinal iron absorption and relevant diseases: an update].[肠道铁吸收及相关疾病:最新进展]
Zhonghua Yi Xue Za Zhi. 2001 Dec 25;81(24):1533-5.
10
Iron Imports. V. Transport of iron through the intestinal epithelium.铁的吸收。五、铁通过肠上皮的转运
Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G417-22. doi: 10.1152/ajpgi.00489.2005.

引用本文的文献

1
Expression kinetics of natural resistance associated macrophage protein (NRAMP) genes in Salmonella Typhimurium-infected chicken.鼠伤寒沙门氏菌感染鸡中天然抗性相关巨噬细胞蛋白(NRAMP)基因的表达动力学
BMC Vet Res. 2018 Jun 8;14(1):180. doi: 10.1186/s12917-018-1510-4.
2
Infection with Mycobacterium avium differentially regulates the expression of iron transport protein mRNA in murine peritoneal macrophages.鸟分枝杆菌感染对小鼠腹腔巨噬细胞中铁转运蛋白mRNA的表达有不同的调节作用。
Infect Immun. 2001 Nov;69(11):6618-24. doi: 10.1128/IAI.69.11.6618-6624.2001.