司来吉兰及其他单胺氧化酶抑制剂的神经保护作用。
Neuroprotection by selegiline and other MAO inhibitors.
作者信息
Stern G
机构信息
Department of Clinical Neurology, University College, London Hospitals, United Kingdom.
出版信息
J Neural Transm Suppl. 1998;52:99-107. doi: 10.1007/978-3-7091-6499-0_12.
PMID:9564613
Abstract
A proposal for the nomination of the father of monoamine oxidase inhibitors is presented. A brief history of the human clinical pharmacology of selegiline is considered including the results of two major prospective ongoing clinical trials and recent evidence on the effects of sustained selegiline therapy on postural blood pressures in parkinsonians is discussed.
摘要
本文提出了一项关于单胺氧化酶抑制剂之父提名的提议。文中探讨了司来吉兰人体临床药理学的简要历史，包括两项正在进行的主要前瞻性临床试验的结果，以及近期关于司来吉兰持续治疗对帕金森病患者体位血压影响的证据。
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