Barlow D H
Department of Obstetrics and Gynaecology, University of Oxford, England.
J Reprod Med. 1998 Mar;43(3 Suppl):245-51.
GnRH agonists (GnRH-a) were introduced into in vitro fertilization (IVF) superovulation regimens in the late 1980s and have become established as a component of standard regimens in most centers worldwide. Each style of GnRH-a regimen (long, short or ultrashort) is associated with particular advantages and disadvantages. In general the "long protocol" approach tends to be the most widely used. The pros and cons of these different approaches are discussed, as are issues concerned with the management and safety of GnRH-a regimens in IVF.
促性腺激素释放激素激动剂（GnRH-a）于20世纪80年代末被引入体外受精（IVF）超排卵方案，并已成为全球大多数中心标准方案的一个组成部分。每种GnRH-a方案（长效、短效或超短效）都有其特定的优缺点。一般来说，“长效方案”方法使用最为广泛。本文讨论了这些不同方法的利弊，以及IVF中GnRH-a方案的管理和安全性问题。
